Journal: Diagnostics
Article Title: Urinary Metabolomic Analysis of Prostate Cancer by UPLC-FTMS and UPLC-Ion Trap MS n
doi: 10.3390/diagnostics13132270
Figure Lengend Snippet: ( a ) A typical base peak chromatogram of BPH urine. The four arrows indicate the retention times of four selected features. They were m / z 205.0685, 334.1126, 551.2124, and 407.2798 at retention times of 2.2, 10.3, 12.1, and 16.8 min, respectively. These four features are different in retention times, molecular weights, and ion intensities. They were used to evaluate the stability of the UPLC-FTMS. They were finally identified as D-mannitol, N 2 , N 2 -dimethylguanosine, phenylacetyl L-glutamine, and 7-ketodeoxycholic acid, respectively. The detected parameters are listed. ( b ) The PCA plot of BPH and Her urines. The symbol (Δ) denotes BPH, (x) Her, and (O) QC. The QC was made by mixing an equal amount of each urine sample.
Article Snippet: N 2 , N 2 -Dimethylguanosine, 7-Ketodeoxycholic acid, and Phenylacetyl L-glutamine were purchased from Toronto Research Chemicals Inc. (North York, ON, Canada).
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